Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

MHC class II molecules usually bind peptides in the endocytic pathway, but can also present endogenous peptides from newly synthesized proteins in a chloroquine-insensitive manner, suggesting that peptide binding might occur in the endoplasmic reticulum (ER). We used in vitro translation of HLA-DR1...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Bijlmakers, M J, Benaroch, P, Ploegh, H L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395144/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8013468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06560.x
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