Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

MHC class II molecules usually bind peptides in the endocytic pathway, but can also present endogenous peptides from newly synthesized proteins in a chloroquine-insensitive manner, suggesting that peptide binding might occur in the endoplasmic reticulum (ER). We used in vitro translation of HLA-DR1...

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Bibliografiska uppgifter

I publikationen:	EMBO J
Huvudupphov:	Bijlmakers, M J, Benaroch, P, Ploegh, H L
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Nature Publishing Group 1994
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395144/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8013468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06560.x
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