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G-protein-coupled receptor kinase-6 interacts with Activator of G-protein signaling-3 to regulate CXCR2-mediated cellular functions
The interleukin-8 (IL-8/CXCL8) receptors, CXCR1 and CXCR2, couple to Gα(i) to induce leukocyte recruitment and activation at sites of inflammation. We have recently shown that CXCR1 couples predominantly to the G protein-coupled receptor (GPCR) kinase-2 (GRK2) whereas CXCR2 interacts with GRK6 to re...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950967/ https://ncbi.nlm.nih.gov/pubmed/24510965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301875 |
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