Susceptibility of Different Hepatitis B Virus Isolates to Interferon-Alpha in a Mouse Model Based on Hydrodynamic Injection

Interferon alpha (IFN-α) is commonly used for the treatment of chronic hepatitis B (CHB) patients. Many factors including viral genetics may determine the outcome of IFN-α therapy. In this study, we tested whether the expression of IFN-α directly in the liver inhibits HBV gene expression and replica...

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Главные авторы: Song, Jingjiao, Zhou, Yun, Li, Sheng, Wang, Baoju, Zheng, Xin, Wu, Jun, Gibbert, Kathrin, Dittmer, Ulf, Lu, Mengji, Yang, Dongliang
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950299/
https://ncbi.nlm.nih.gov/pubmed/24618716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090977
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