Poly(I:C) Treatment Leads to Interferon-Dependent Clearance of Hepatitis B Virus in a Hydrodynamic Injection Mouse Model

We have previously shown that poly(I:C) activates murine hepatic cells to produce interferon (IFN) and suppresses hepatitis B virus (HBV) replication in vitro. Therefore, we addressed whether poly(I:C) is able to induce the clearance of HBV in vivo. The chronic HBV replication mouse model was establ...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wu, Jun, Huang, Shunmei, Zhao, Xiaoli, Chen, Mingfa, Lin, Yong, Xia, Youchen, Sun, Chan, Yang, Xuecheng, Wang, Junzhong, Guo, Yan, Song, Jingjiao, Zhang, Ejuan, Wang, Baoju, Zheng, Xin, Schlaak, Joerg F., Lu, Mengji, Yang, Dongliang
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178898/
https://ncbi.nlm.nih.gov/pubmed/24920792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00996-14
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