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Myocardial contraction and hyaluronic acid mechanotransduction in epithelial-to-mesenchymal transformation of endocardial cells

Epithelial-to-mesenchymal transition (EMT) of endocardial cells is a critical initial step in the formation of heart valves. The collagen gel in vitro model has provided significant information on the role of growth factors regulating EMT but has not permitted investigation of mechanical factors. Th...

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Detalhes bibliográficos
Main Authors: Sewell-Loftin, Mary Kathryn, DeLaughter, Daniel M., Peacock, Jon R., Brown, Christopher B., Baldwin, H. Scott, Barnett, Joey V., Merryman, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950274/
https://ncbi.nlm.nih.gov/pubmed/24433835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.12.051
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