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ENDOCARDIAL CELL EPITHELIAL-MESENCHYMAL TRANSFORMATION REQUIRES TYPE III TGFβ RECEPTOR INTERACTION WITH GIPC
An early event in heart valve formation is the epithelial-mesenchymal transformation (EMT) of a subpopulation of endothelial cells in specific regions of the heart tube, the endocardial cushions. The Type III TGFβ receptor (TGFβR3) is required for TGFβ2- or BMP-2-stimulated EMT in atrioventricular e...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208316/ https://ncbi.nlm.nih.gov/pubmed/21945156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.09.006 |
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