Functional and biochemical association of Hck with the LIF/IL-6 receptor signal transducing subunit gp130 in embryonic stem cells.

The role played by the Src-related tyrosine kinase, Hck, in embryonic stem (ES) cell differentiation was investigated by replacing a conserved C-terminally located tyrosine with phenylalanine by gene targeting. Targeted ES cells display a 7- to 9-fold elevation in constitutive Hck kinase activity an...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Ernst, M, Gearing, D P, Dunn, A R
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8156996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06420.x
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