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Glycine receptor mouse mutants: model systems for human hyperekplexia
Human hyperekplexia is a neuromotor disorder caused by disturbances in inhibitory glycine-mediated neurotransmission. Mutations in genes encoding for glycine receptor subunits or associated proteins, such as GLRA1, GLRB, GPHN and ARHGEF9, have been detected in patients suffering from hyperekplexia....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949644/ https://ncbi.nlm.nih.gov/pubmed/23941355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12335 |
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