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Glycine receptor mouse mutants: model systems for human hyperekplexia

Human hyperekplexia is a neuromotor disorder caused by disturbances in inhibitory glycine-mediated neurotransmission. Mutations in genes encoding for glycine receptor subunits or associated proteins, such as GLRA1, GLRB, GPHN and ARHGEF9, have been detected in patients suffering from hyperekplexia....

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Autori principali: Schaefer, Natascha, Langlhofer, Georg, Kluck, Christoph J, Villmann, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell publishing Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949644/
https://ncbi.nlm.nih.gov/pubmed/23941355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12335
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