The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

Heterodimers of retinoid X receptor (RXR) and retinoic acid receptor (RAR) bind preferentially to directly repeated elements with spacing of two (DR2) or five (DR5) base pairs, due to the specific heterocooperative interaction of their DNA binding domains (DBDs) on these elements. We have demonstrat...

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Xehetasun bibliografikoak

Argitaratua izan da:	EMBO J
Egile Nagusiak:	Zechel, C, Shen, X Q, Chen, J Y, Chen, Z P, Chambon, P, Gronemeyer, H
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Publishing Group 1994
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8137826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06396.x
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