The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

Heterodimers of retinoid X receptor (RXR) and retinoic acid receptor (RAR) bind preferentially to directly repeated elements with spacing of two (DR2) or five (DR5) base pairs, due to the specific heterocooperative interaction of their DNA binding domains (DBDs) on these elements. We have demonstrat...

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Detaylı Bibliyografya

Yayımlandı:	EMBO J
Asıl Yazarlar:	Zechel, C, Shen, X Q, Chen, J Y, Chen, Z P, Chambon, P, Gronemeyer, H
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Nature Publishing Group 1994
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8137826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06396.x
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