The quaternary architecture of RARβ–RXRα heterodimer facilitates domain–domain signal transmission
Nuclear receptors (NR) are multidomain proteins, which makes their crystallization challenging. Here the authors present the crystal structure of the retinoic acid receptor β–retinoic X receptor α (RARβ–RXRα) heterodimer bound to DNA, ligands and coactivator peptides, which shows that NR quaternary...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Portfolio
2017-10-01
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| シリーズ: | Nature Communications |
| オンライン･アクセス: | https://doi.org/10.1038/s41467-017-00981-y |
| タグ: |
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