Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms

Autoantibody formation is essential for the development of certain autoimmune diseases like rheumatoid arthritis (RA). Anti-type II collagen (CII) antibodies are found in RA patients; they interact with cartilage in vivo and are often highly pathogenic in the mouse. Autoreactivity to CII is directed...

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Detalhes bibliográficos
Main Authors: Raposo, Bruno, Dobritzsch, Doreen, Ge, Changrong, Ekman, Diana, Xu, Bingze, Lindh, Ingrid, Förster, Michael, Uysal, Hüseyin, Nandakumar, Kutty Selva, Schneider, Gunter, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949579/
https://ncbi.nlm.nih.gov/pubmed/24534192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130968
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