Neural correlates of rapid antidepressant response to ketamine in bipolar disorder

OBJECTIVES: Ketamine, an N-methyl D-aspartate (NMDA) antagonist, has rapid antidepressant effects in depressed subjects with bipolar disorder (BD). Evidence supports a role for the glutamatergic system in the pathophysiology of BD. This double-blind, randomized, cross-over study sought to determine...

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Detalhes bibliográficos
Main Authors: Nugent, Allison C, Diazgranados, Nancy, Carlson, Paul J, Ibrahim, Lobna, Luckenbaugh, David A, Brutsche, Nancy, Herscovitch, Peter, Drevets, Wayne C, Zarate, Carlos A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949142/
https://ncbi.nlm.nih.gov/pubmed/24103187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bdi.12118
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