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Neural mechanisms of antidepressant efficacy of the dopamine receptor agonist pramipexole in treatment of bipolar depression

The D(2)/D(3) receptor agonist pramipexole has clinical efficacy as an antidepressant, but its neural mechanisms are unknown. We used (18)FDG-PET to investigate the cerebral metabolic effects of pramipexole augmentation of mood stabilizers in bipolar II depression. Fifteen bipolar II depressed patie...

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Detalhes bibliográficos
Main Authors: Mah, Linda, Zarate, Carlos A., Nugent, Allison C., Singh, Jaskaran B., Manji, Husseini K., Drevets, Wayne C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085539/
https://ncbi.nlm.nih.gov/pubmed/21029512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145710001203
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