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SHANK3 AS A POTENTIAL BIOMARKER OF ANTIDEPRESSANT RESPONSE TO KETAMINE AND ITS NEURAL CORRELATES IN BIPOLAR DEPRESSION

BACKGROUND: Shank3, a post-synaptic density protein involved in N-methyl-D-aspartate (NMDA) receptor tethering and dendritic spine rearrangement, is implicated in the pathophysiology of bipolar disorder. We hypothesized that elevated baseline plasma Shank3 levels might predict antidepressant respons...

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Detalhes bibliográficos
Publicado no:J Affect Disord
Main Authors: Ortiz, Robin, Niciu, Mark J., Lukkahati, Nada, Saligan, Leorey N., Nugent, Allison C., Luckenbaugh, David A., Machado-Vieira, Rodrigo, Zarate, Carlos A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400209/
https://ncbi.nlm.nih.gov/pubmed/25451430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2014.09.015
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