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Regulation of T Cell Differentiation and Alloimmunity by the Cyclin-Dependent Kinase Inhibitor p18ink4c

Cellular proliferation in response to mitogenic stimuli is negatively regulated by the Cip/Kip and the Ink4 families of cyclin-dependent kinase (CDK) inhibitors. Several of these proteins are elevated in anergic T cells, suggesting a potential role in the induction or maintenance of tolerance. Our p...

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Autori principali: Rowell, Emily A., Wang, Liqing, Chunder, Neelanjana, Hancock, Wayne W., Wells, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948896/
https://ncbi.nlm.nih.gov/pubmed/24614758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091587
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