Cyclin-dependent kinase 2 controls peripheral immune tolerance

Adaptive immunity requires signals from both the T cell antigen receptor and the costimulatory molecule CD28. These receptors activate multiple signaling pathways, including the cyclin-dependent kinase (CDK) cascade, and antigenic signals in the absence of costimulation results in a tolerant state t...

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Bibliographic Details
Main Authors:	Chunder, Neelanjana, Wang, Liqing, Chen, Chunxia, Hancock, Wayne W., Wells, Andrew D.
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3518671/ https://ncbi.nlm.nih.gov/pubmed/23136201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202313
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Cyclin-dependent kinase 2 controls peripheral immune tolerance

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