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Cyclin-dependent kinase 2 controls peripheral immune tolerance
Adaptive immunity requires signals from both the T cell antigen receptor and the costimulatory molecule CD28. These receptors activate multiple signaling pathways, including the cyclin-dependent kinase (CDK) cascade, and antigenic signals in the absence of costimulation results in a tolerant state t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518671/ https://ncbi.nlm.nih.gov/pubmed/23136201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202313 |
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