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Foxp3 Protein Stability Is Regulated by Cyclin-dependent Kinase 2
Foxp3 is a transcription factor required for the development of regulatory T cells (Treg). Mice and humans with a loss of Foxp3 function suffer from uncontrolled autoimmunity and inflammatory disease. Expression of Foxp3 is necessary for the anti-inflammatory capacity of Treg, but whether Foxp3 acti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750148/ https://ncbi.nlm.nih.gov/pubmed/23853094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.467704 |
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