Foxp3 Protein Stability Is Regulated by Cyclin-dependent Kinase 2

Foxp3 is a transcription factor required for the development of regulatory T cells (Treg). Mice and humans with a loss of Foxp3 function suffer from uncontrolled autoimmunity and inflammatory disease. Expression of Foxp3 is necessary for the anti-inflammatory capacity of Treg, but whether Foxp3 acti...

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Bibliografiske detaljer
Main Authors: Morawski, Peter A., Mehra, Parul, Chen, Chunxia, Bhatti, Tricia, Wells, Andrew D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750148/
https://ncbi.nlm.nih.gov/pubmed/23853094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.467704
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