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DIFFERENTIAL REGULATION OF CYCLIN-DEPENDENT KINASE INHIBITORS IN NEUROBLASTOMA CELLS

Gastrin-releasing peptide (GRP) and its receptor (GRP-R) are highly expressed in undifferentiated neuroblastoma, and they play critical roles in oncogenesis. We previously reported that GRP activates the PI3K/AKT signaling pathway to promote DNA synthesis and cell cycle progression in neuroblastoma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qiao, Lan, Paul, Pritha, Lee, Sora, Qiao, Jingbo, Wang, Yongsheng, Chung, Dai H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754446/
https://ncbi.nlm.nih.gov/pubmed/23618860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.04.023
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