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Targeting Aurora Kinase a Downregulates Cell Proliferation and Angiogenesis in Neuroblastoma

PURPOSE: Aurora kinase A (AURKA) overexpression is associated with poor prognosis in neuroblastoma and has been described to upregulate VEGF in gastric cancer cells. However, the exact role of AURKA in the regulation of neuroblastoma tumorigenesis remains unknown. We hypothesize that AURKA-mediated...

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Détails bibliographiques
Auteurs principaux: Romain, Carmelle, Paul, Pritha, Kim, Kwang Woon, Lee, Sora, Qiao, Jingbo, Chung, Dai H.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183462/
https://ncbi.nlm.nih.gov/pubmed/24439602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2013.09.051
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