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Targeting Aurora Kinase a Downregulates Cell Proliferation and Angiogenesis in Neuroblastoma

PURPOSE: Aurora kinase A (AURKA) overexpression is associated with poor prognosis in neuroblastoma and has been described to upregulate VEGF in gastric cancer cells. However, the exact role of AURKA in the regulation of neuroblastoma tumorigenesis remains unknown. We hypothesize that AURKA-mediated...

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Detalhes bibliográficos
Main Authors: Romain, Carmelle, Paul, Pritha, Kim, Kwang Woon, Lee, Sora, Qiao, Jingbo, Chung, Dai H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183462/
https://ncbi.nlm.nih.gov/pubmed/24439602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2013.09.051
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