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LAP (NF-IL-6), a tissue-specific transcriptional activator, is an inhibitor of hepatoma cell proliferation.

During postnatal liver development, LAP (NF-IL-6, C/EBP beta) expression and hepatocyte proliferation are mutually exclusive. In addition to transactivating liver-specific genes, LAP, but not C/EBP alpha, arrests the cell cycle before the G1/S boundary in hepatoma cells. LIP, a liver-inhibitory prot...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Buck, M, Turler, H, Chojkier, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC394884/
https://ncbi.nlm.nih.gov/pubmed/7906646
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