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Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.

Single binding sites for transcription factors NF-IL6 and NF-kappa B are present in the promoter of the interleukin (IL) 6 gene. Previous studies of internally deleted promoter mutants demonstrated that these two sites are important for the transcriptional regulation of this gene. In this report, we...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Matsusaka, T, Fujikawa, K, Nishio, Y, Mukaida, N, Matsushima, K, Kishimoto, T, Akira, S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1993
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Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10193
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