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LAP (NF-IL6) transactivates the collagen alpha 1(I) gene from a 5' regulatory region.

Although collagen is known to enhance hepatocyte differentiation and hepatocytes produce collagen in vivo, the transcriptional factors responsible for collagen type I gene expression in hepatic cells are not known. LAP (Liver Activator Protein) is a member of the C/EBP family, which in differentiate...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Houglum, K, Buck, M, Adir, V, Chojkier, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296161/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117400
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