Approaches to Improve the Oral Bioavailability and Effects of Novel Anticancer Drugs Berberine and Betulinic Acid

BACKGROUND: The poor bioavailability of Berberine (BBR) and Betulinic acid (BA) limits the development of these promising anticancer agents for clinical use. In the current study, BBR and BA in spray dried (SD) mucoadhesive microparticle formulations were prepared. METHODS: A patented dual channel s...

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Hlavní autoři: Godugu, Chandraiah, Patel, Apurva R., Doddapaneni, Ravi, Somagoni, Jaganmohan, Singh, Mandip
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948684/
https://ncbi.nlm.nih.gov/pubmed/24614362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089919
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