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Approaches to Improve the Oral Bioavailability and Effects of Novel Anticancer Drugs Berberine and Betulinic Acid

BACKGROUND: The poor bioavailability of Berberine (BBR) and Betulinic acid (BA) limits the development of these promising anticancer agents for clinical use. In the current study, BBR and BA in spray dried (SD) mucoadhesive microparticle formulations were prepared. METHODS: A patented dual channel s...

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Bibliografische gegevens
Hoofdauteurs: Godugu, Chandraiah, Patel, Apurva R., Doddapaneni, Ravi, Somagoni, Jaganmohan, Singh, Mandip
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948684/
https://ncbi.nlm.nih.gov/pubmed/24614362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089919
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