Prokaryotic Soluble Overexpression and Purification of Bioactive Human Growth Hormone by Fusion to Thioredoxin, Maltose Binding Protein, and Protein Disulfide Isomerase

Human growth hormone (hGH) is synthesized by somatotroph cells of the anterior pituitary gland and induces cell proliferation and growth. This protein has been approved for the treatment of various conditions, including hGH deficiency, chronic renal failure, and Turner syndrome. Efficient production...

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Bibliografski detalji
Glavni autori: Nguyen, Minh Tan, Koo, Bon-Kyung, Thi Vu, Thu Trang, Song, Jung-A, Chong, Seon-Ha, Jeong, Boram, Ryu, Han-Bong, Moh, Sang-Hyun, Choe, Han
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948679/
https://ncbi.nlm.nih.gov/pubmed/24614134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089038
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