Prokaryotic Soluble Overexpression and Purification of Bioactive Human Growth Hormone by Fusion to Thioredoxin, Maltose Binding Protein, and Protein Disulfide Isomerase

Human growth hormone (hGH) is synthesized by somatotroph cells of the anterior pituitary gland and induces cell proliferation and growth. This protein has been approved for the treatment of various conditions, including hGH deficiency, chronic renal failure, and Turner syndrome. Efficient production...

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Main Authors: Nguyen, Minh Tan, Koo, Bon-Kyung, Thi Vu, Thu Trang, Song, Jung-A, Chong, Seon-Ha, Jeong, Boram, Ryu, Han-Bong, Moh, Sang-Hyun, Choe, Han
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948679/
https://ncbi.nlm.nih.gov/pubmed/24614134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089038
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