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Short-term hypoxic vasodilation in vivo is mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction

Local increases in blood flow – ‘hypoxic vasodilation’ – confer cellular protection in the face of reduced oxygen delivery. The physiological relevance of this response is well established, yet ongoing controversy surrounds its underlying mechanisms. We sought to confirm that early hypoxic vasodilat...

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Autors principals: Umbrello, Michele, Dyson, Alex, Pinto, Bernardo Bollen, Fernandez, Bernadette O, Simon, Verena, Feelisch, Martin, Singer, Mervyn
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948563/
https://ncbi.nlm.nih.gov/pubmed/24396056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.255687
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