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Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action

The plasma level of NO(x), i.e., the sum of NO(2)(−) and NO(3)(−), is frequently used to assess NO bioavailability in vivo. However, little is known about the kinetics of NO conversion to these metabolites under physiological conditions. Moreover, plasma nitrite recently has been proposed to represe...

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Detalhes bibliográficos
Main Authors: Lauer, Thomas, Preik, Michael, Rassaf, Tienush, Strauer, Bodo E., Deussen, Andreas, Feelisch, Martin, Kelm, Malte
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60136/
https://ncbi.nlm.nih.gov/pubmed/11606734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221381098
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