Nitrite Regulates Hypoxic Vasodilation via Myoglobin–Dependent Nitric Oxide Generation

BACKGROUND: Hypoxic vasodilation is a physiological response to low oxygen (O(2)) tension that increases blood supply to match metabolic demands. While this response has been characterized for more than 100 years, the underlying hypoxic sensing and effector signaling mechanisms remain uncertain. We...

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Detalhes bibliográficos
Main Authors: Totzeck, Matthias, Hendgen-Cotta, Ulrike B., Luedike, Peter, Berenbrink, Michael, Klare, Johann P., Steinhoff, Heinz-Juergen, Semmler, Dominik, Shiva, Sruti, Williams, Daryl, Kipar, Anja, Gladwin, Mark T., Schrader, Juergen, Kelm, Malte, Cossins, Andrew R., Rassaf, Tienush
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410747/
https://ncbi.nlm.nih.gov/pubmed/22685116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.087155
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