Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

The nitrite anion is reduced to nitric oxide (NO(•)) as oxygen tension decreases. Whereas this pathway modulates hypoxic NO(•) signaling and mitochondrial respiration and limits myocardial infarction in mammalian species, the pathways to nitrite bioactivation remain uncertain. Studies suggest that h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hendgen-Cotta, Ulrike B., Merx, Marc W., Shiva, Sruti, Schmitz, Joel, Becher, Stefanie, Klare, Johann P., Steinhoff, Heinz-Jürgen, Goedecke, Axel, Schrader, Jürgen, Gladwin, Mark T., Kelm, Malte, Rassaf, Tienush
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481313/
https://ncbi.nlm.nih.gov/pubmed/18632562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801336105
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