Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

The nitrite anion is reduced to nitric oxide (NO(•)) as oxygen tension decreases. Whereas this pathway modulates hypoxic NO(•) signaling and mitochondrial respiration and limits myocardial infarction in mammalian species, the pathways to nitrite bioactivation remain uncertain. Studies suggest that h...

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Detalhes bibliográficos
Main Authors: Hendgen-Cotta, Ulrike B., Merx, Marc W., Shiva, Sruti, Schmitz, Joel, Becher, Stefanie, Klare, Johann P., Steinhoff, Heinz-Jürgen, Goedecke, Axel, Schrader, Jürgen, Gladwin, Mark T., Kelm, Malte, Rassaf, Tienush
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481313/
https://ncbi.nlm.nih.gov/pubmed/18632562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801336105
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