Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

The nitrite anion is reduced to nitric oxide (NO(•)) as oxygen tension decreases. Whereas this pathway modulates hypoxic NO(•) signaling and mitochondrial respiration and limits myocardial infarction in mammalian species, the pathways to nitrite bioactivation remain uncertain. Studies suggest that h...

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Détails bibliographiques
Auteurs principaux: Hendgen-Cotta, Ulrike B., Merx, Marc W., Shiva, Sruti, Schmitz, Joel, Becher, Stefanie, Klare, Johann P., Steinhoff, Heinz-Jürgen, Goedecke, Axel, Schrader, Jürgen, Gladwin, Mark T., Kelm, Malte, Rassaf, Tienush
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481313/
https://ncbi.nlm.nih.gov/pubmed/18632562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801336105
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