Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

The nitrite anion is reduced to nitric oxide (NO(•)) as oxygen tension decreases. Whereas this pathway modulates hypoxic NO(•) signaling and mitochondrial respiration and limits myocardial infarction in mammalian species, the pathways to nitrite bioactivation remain uncertain. Studies suggest that h...

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Detalles Bibliográficos
Autores principales: Hendgen-Cotta, Ulrike B., Merx, Marc W., Shiva, Sruti, Schmitz, Joel, Becher, Stefanie, Klare, Johann P., Steinhoff, Heinz-Jürgen, Goedecke, Axel, Schrader, Jürgen, Gladwin, Mark T., Kelm, Malte, Rassaf, Tienush
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481313/
https://ncbi.nlm.nih.gov/pubmed/18632562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801336105
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