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Nitrite directly vasodilates hypoxic vasculature via nitric oxide-dependent and -independent pathways

BACKGROUND AND PURPOSE: It is postulated that nitrite requires reduction to nitric oxide in order to exert its relaxant effect upon isolated hypoxic vessels. Herein, we evaluate the relative contribution of nitric oxide and characterize the downstream mechanisms of nitrite-induced vasorelaxation. EX...

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Détails bibliographiques
Auteurs principaux: Pinder, AG, Pittaway, E, Morris, K, James, PE
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765305/
https://ncbi.nlm.nih.gov/pubmed/19594749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00340.x
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