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Hemoglobin, nitric oxide and molecular mechanisms of hypoxic vasodilation

The protected transport of nitric oxide (NO) by hemoglobin (Hb) links the metabolic activity of working tissue to the regulation of its local blood supply through hypoxic vasodilation. This physiologic mechanism is allosterically coupled to the O(2) saturation of Hb and involves the covalent binding...

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Detalhes bibliográficos
Main Authors: Allen, Barry W., Stamler, Jonathan S., Piantadosi, Claude A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785508/
https://ncbi.nlm.nih.gov/pubmed/19781996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2009.08.002
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