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Nitrite directly vasodilates hypoxic vasculature via nitric oxide-dependent and -independent pathways

BACKGROUND AND PURPOSE: It is postulated that nitrite requires reduction to nitric oxide in order to exert its relaxant effect upon isolated hypoxic vessels. Herein, we evaluate the relative contribution of nitric oxide and characterize the downstream mechanisms of nitrite-induced vasorelaxation. EX...

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Autors principals: Pinder, AG, Pittaway, E, Morris, K, James, PE
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765305/
https://ncbi.nlm.nih.gov/pubmed/19594749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00340.x
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