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PI 3-kinase: structural and functional analysis of intersubunit interactions.

Phosphatidylinositol (PI) 3-kinase has an 85 kDa subunit (p85 alpha) which mediates its association with activated protein tyrosine kinase receptors through SH2 domains, and an 110 kDa subunit (p110) which has intrinsic catalytic activity. Here p85 alpha and a related protein p85 beta are shown to f...

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Hlavní autoři: Dhand, R, Hara, K, Hiles, I, Bax, B, Gout, I, Panayotou, G, Fry, M J, Yonezawa, K, Kasuga, M, Waterfield, M D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC394840/
https://ncbi.nlm.nih.gov/pubmed/8313896
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