Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach.

The interaction between SH2 domains and phosphotyrosine-containing sequences was examined by real-time measurements of kinetic parameters. The SH2 domains of the p85 subunit of the phosphatidylinositol 3-kinase as well as of other signaling molecules were expressed in bacteria as glutathione S-trans...

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Detalhes bibliográficos
Main Authors: Panayotou, G, Gish, G, End, P, Truong, O, Gout, I, Dhand, R, Fry, M J, Hiles, I, Pawson, T, Waterfield, M D
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359826/
https://ncbi.nlm.nih.gov/pubmed/8388538
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