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PI 3-kinase: structural and functional analysis of intersubunit interactions.

Phosphatidylinositol (PI) 3-kinase has an 85 kDa subunit (p85 alpha) which mediates its association with activated protein tyrosine kinase receptors through SH2 domains, and an 110 kDa subunit (p110) which has intrinsic catalytic activity. Here p85 alpha and a related protein p85 beta are shown to f...

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Detalhes bibliográficos
Main Authors: Dhand, R, Hara, K, Hiles, I, Bax, B, Gout, I, Panayotou, G, Fry, M J, Yonezawa, K, Kasuga, M, Waterfield, M D
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394840/
https://ncbi.nlm.nih.gov/pubmed/8313896
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