Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns.

Specific phosphorylated tyrosine residues in the kinase insert region of the human platelet-derived-growth-factor beta-receptor mediate the formation of multienzyme complexes with this receptor. When phosphorylated, tyrosine residue 751 within the kinase insert region mediates binding of PtdIns 3-ki...

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Hlavní autoři: Fry, M J, Panayotou, G, Dhand, R, Ruiz-Larrea, F, Gout, I, Nguyen, O, Courtneidge, S A, Waterfield, M D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132023/
https://ncbi.nlm.nih.gov/pubmed/1281404
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