Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

The t(3;21)(q26;q22) translocation, which is one of the consistent chromosomal abnormalities found in blastic crisis of chronic myelocytic leukemia (CML), is thought to play an important role in the leukemic progression of CML to an acute blastic crisis phase. The AML1 gene, which is located at the...

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Hlavní autoři: Mitani, K, Ogawa, S, Tanaka, T, Miyoshi, H, Kurokawa, M, Mano, H, Yazaki, Y, Ohki, M, Hirai, H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC394839/
https://ncbi.nlm.nih.gov/pubmed/8313895
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