Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

The t(3;21)(q26;q22) translocation, which is one of the consistent chromosomal abnormalities found in blastic crisis of chronic myelocytic leukemia (CML), is thought to play an important role in the leukemic progression of CML to an acute blastic crisis phase. The AML1 gene, which is located at the...

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Autores principales: Mitani, K, Ogawa, S, Tanaka, T, Miyoshi, H, Kurokawa, M, Mano, H, Yazaki, Y, Ohki, M, Hirai, H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC394839/
https://ncbi.nlm.nih.gov/pubmed/8313895
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