The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability.

Ítems similars

• An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.
  per: Tanaka, T, et al.
  Publicat: (1995)
• Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias.
  per: Tanaka, T, et al.
  Publicat: (1995)
• The Corepressor mSin3A Regulates Phosphorylation-Induced Activation, Intranuclear Location, and Stability of AML1
  per: Imai, Yoichi, et al.
  Publicat: (2004)
• Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.
  per: Mitani, K, et al.
  Publicat: (1994)
• Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia.
  per: Miyoshi, H, et al.
  Publicat: (1995)