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Dissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusion

The envelope glycoprotein gp41 mediates the process of membrane fusion that enables entry of the HIV-1 virus into the host cell. The actual fusion process involves a switch from a homotrimeric prehairpin intermediate conformation, consisting of parallel coiled-coil helices, to a postfusion state whe...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Roche, Julien, Louis, John M., Grishaev, Alexander, Ying, Jinfa, Bax, Adriaan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948261/
https://ncbi.nlm.nih.gov/pubmed/24550514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401397111
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