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An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells
In the thymus, interactions with both cortical and medullary microenvironments regulate the development of self-tolerant conventional CD4(+) and CD8(+) αβT cells expressing a wide range of αβTCR specificities. Additionally, the cortex is also required for the development of invariant NKT (iNKT) cell...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AAI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948113/ https://ncbi.nlm.nih.gov/pubmed/24510964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303057 |
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