Nodal Promotes the Self-Renewal of Human Colon Cancer Stem Cells via an Autocrine Manner through Smad2/3 Signaling Pathway

Colorectal cancer is one of the most common and fatal tumors. However, molecular mechanisms underlying carcinogenesis of colorectal cancer remain largely undefined. Here, we explored the expression and function of Nodal in colon cancer stem cells (CCSCs). Nodal and its receptors were present in nume...

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Bibliographische Detailangaben
Hauptverfasser: Gong, Yuehua, Guo, Ying, Hai, Yanan, Yang, Hao, Liu, Yang, Yang, Shi, Zhang, Zhenzhen, Ma, Meng, Liu, Linhong, Li, Zheng, He, Zuping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947734/
https://ncbi.nlm.nih.gov/pubmed/24696849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/364134
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