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Smad4 is critical for self-renewal of hematopoietic stem cells

Members of the transforming growth factor β (TGF-β) superfamily of growth factors have been shown to regulate the in vitro proliferation and maintenance of hematopoietic stem cells (HSCs). Working at a common level of convergence for all TGF-β superfamily signals, Smad4 is key in orchestrating these...

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Detalhes bibliográficos
Main Authors: Karlsson, Göran, Blank, Ulrika, Moody, Jennifer L., Ehinger, Mats, Singbrant, Sofie, Deng, Chu-Xia, Karlsson, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137898/
https://ncbi.nlm.nih.gov/pubmed/17353364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060465
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